This is one we can save. Assigned to a new post, reserved British diplomat Justin Quayle (Ralph Fiennes) relocates to Kenya with his new wife, Tessa (Rachel Weisz), an activist for social justice. She is engaged on a hunt for the people behind a Big Pharma test of a dangerous AIDS drug being conducted on expendable local TB sufferers. Her own child is born dead in an African hospital and a young girl in a neighbouring bed dies after taking the drug. When Tessa is found murdered out in the wilderness, circumstances point to her friend, Dr. Arnold Bluhm (Hubert Koundé), who has been agitating for the truth with her, but it is soon clear that he’s not the killer. Grief-stricken and angry, Justin sets out to uncover who is responsible for Tessa’s murder and in the process, he unearths some disturbing revelations – including that some of his cohorts in Government might be behind it. He also really discovers the woman he married … John le Carré is a remarkable novelist: for five decades he has been writing books that point the finger through the prism of genre and in the Noughties he decided to take aim at the self-appointed God-like pharmaceutical companies that dominate so much of contemporary existence – and survival – and the countries whose internecine deals allow them to kill their own at will. Jeffrey Caine does a great job at filleting the story so it’s clear who the bad guys are – there are degrees of grotesquery here and it’s certainly not kind on African savagery either. A horrifying tale of corruption that, knowing its author, is all too true. Terrifically performed by the leads with good support from Bill Nighy, Pete Postlethwaite and Danny Huston. Directed by Fernando Meirelles. No drug company does something for nothing.